Dynamic Restoration
of the Chronic Wound
Microenvironment

From chronicity toward regeneration.

HEALING EVOLUTIONDAY 0
THE LEAD PRODUCT · TOPICAL THERAPY

First-in-Class
Topical
Hydrogel

A multi-mechanism formulation designed to restore the chronic wound microenvironment through direct, clinician-guided application.

01

RestoreMoves the wound from chronicity toward regeneration.

02

ProtectAddresses infection, inflammation and pain together.

03

RegenerateSupports granulation and re-epithelialization.

Explore the product experience →
Clinician applying transparent UNTECH topical hydrogel to a chronic lower-leg wound
DIRECT APPLICATION Transparent topical hydrogel · Concept presentation
THE MULTI-MECHANISM APPROACH

All-in-onesolution

Chronic wounds are sustained by multiple interconnected factors. UNTECH is designed to address them simultaneously—not one at a time.

THERAPEUTIC SYSTEM
12

Complementary
mechanisms

4

Coordinated
dimensions

1

Integrated
response

01Infection control

Wide-spectrum biofilm inhibition and disruption

Wide-spectrum bacteriostatic and bactericidal action

Protease activity regulation

02Microenvironment restoration

↑ In situ oxygenation

Wound-bed acidification toward a healing pH

Free-radical scavenging

03Tissue regeneration

Displacement from the chronic inflammatory state

↑ Granulation tissue formation

↑ Re-epithelialization

04Patient & wound management

↓ Neuropathic and nociceptive pain

Exudate management

Activation of autolytic debridement

Global access strategy

International
Footprint

Building the right partnerships to take a new wound-care platform from scientific innovation to patients around the world.

Untech international footprint, highlighting the Elea partnership in Latin America and priority global markets
RESEARCH & DEVELOPMENT

Science-driven
Patient-centered

Our therapy is the result of years of research and development—guided by one principle: create the best possible treatment for patients.

01
Scientific rigor

Every stage is carefully refined around the biological complexity of chronic wounds.

02
Real-world relevance

Development decisions reflect the challenges clinicians and patients face every day.

03
Quality at scale

Designed for consistent development under rigorous GMP standards.

Excellence in science only matters when it delivers real outcomes for patients.
CLOSED STRATEGIC PARTNERSHIP · LATIN AMERICA

Untech + Elea.Latin America, secured.

A closed partnership with one of Latin America’s leading pharmaceutical companies.

From development and regulatory execution to manufacturing, commercialization and patient access.

STATUSClosed strategic partnership
REGIONLatin America
PATHWAYDevelopment to patient access
Explore Elea Pharma Group ↗
Elea pharmaceutical production facility
UNTECH+Elea Closed Strategic PartnershipLATIN AMERICA
Doctor speaking with an older patient during a clinical consultation
THE HUMAN COST OF CHRONIC WOUNDS
GLOBAL HEALTH CHALLENGE

Global unmet
medical need.

Every 20 secondssomeone loses a limb due to a chronic wound.

For millions of people, today’s standard of care still manages the wound without resolving the disease that keeps it chronic.

167Mpeople with diabetes are estimated to develop diabetic foot ulcers
1 in 3may become hard-to-heal chronic wounds
1 in 5hard-to-heal diabetic wound cases may result in amputation

The burden extends across diabetic foot ulcers, venous leg ulcers and pressure ulcers—bringing chronic pain, disability and the risk of amputation.

€80–90Bannual spend treating chronic wounds
across Europe and the US
THE COST OF THE STATUS QUO

Current treatments remain costly
and don’t ensure healing.

A large inefficient marketready for disruption.
THE PROBLEM / 01CHRONIC WOUND CARE

Chronic &
hard-to-heal
wounds.

A global problem that crosses geographies and socioeconomic groups.

The burden is growing, driven by diabetes, obesity and population ageing. For millions of patients, a wound becomes more than a local injury: it can remain open when the body's normal repair process is disrupted.

120M+
INDICATIVE GLOBAL SCALE

People potentially affected by chronic and hard-to-heal wounds, depending on how prevalence is defined and estimated.

THREE MAJOR PRESENTATIONS

Different origins.
A shared failure to heal.

Medical illustration of a small diabetic foot ulcer on the sole near the forefoot
MEDICAL ILLUSTRATION
01 / DIABETES

Diabetic foot
ulcers.

Neuropathy, reduced blood flow and repeated pressure can turn a small injury into a persistent foot wound.

Medical illustration of a venous leg ulcer near the ankle
MEDICAL ILLUSTRATION
02 / CIRCULATION

Venous leg
ulcers.

Impaired venous return can sustain swelling and inflammation in the lower leg, slowing tissue repair.

Medical illustration of a small pressure ulcer on an adult heel
MEDICAL ILLUSTRATION
03 / IMMOBILITY

Pressure
ulcers.

Prolonged pressure and shear can reduce tissue perfusion, especially over bony areas such as the heel.

WHY WOUNDS BECOME CHRONIC

Healing is a system.
So is the problem.

Underlying conditions disrupt the body's natural healing process. Diabetes, poor circulation and prolonged pressure create interconnected barriers that can trap wounds in a cycle of chronicity.

01DiabetesMetabolic and immune disruption
02Poor circulationReduced oxygen and nutrient delivery
03Prolonged pressureRepeated tissue stress and injury
WHEN BARRIERS PERSIST

Without addressing these factors together, wounds may enlarge, become infected and, in severe cases, lead to amputation.

Medical illustrations are generated, not patient photographs or diagnostic references. The 120M+ figure is an indicative extrapolation from published estimates of 1–2% global prevalence; methods and definitions vary. Prevalence context · Clinical burden context.

THE SHIFT IN CHRONIC WOUND CARE

Millions of patients don’t need better dressings— they need a new therapeutic paradigm.

FROM PALLIATION→TO HEALING
UNTECH

One Product
Multi Mechanism
Real Healing

PRODUCT EXPERIENCE · CONCEPT

UNTECH
Topical Hydrogel

A new way to approach chronic wound care, designed for direct topical application within a healthcare professional’s treatment plan.

PRESENTATION30 g tube
FORMATTopical hydrogel
INSIDE THE BOX
01

30 g tubeTransparent topical hydrogel in a controlled-dispensing tube.

02

Product informationClinician-directed preparation, application and wound-care guidance.

Living with a chronic wound? A clinician should assess the wound before any treatment is used. This purchase journey is a preview of the future patient experience.

Concept preview · Not currently available for sale

Concept packaging for UNTECH topical hydrogel, 30 gram tube and carton
Future product presentation
UNTECH JOURNAL

News
& updates

Milestones in science, partnerships and the path toward a new standard of chronic wound care.

ABOUT UNTECH · OUR VISION

Built to move
healing forward.

Untech is a drug development company rethinking chronic wound care from the biology up.

We address the wound as an interconnected microenvironment—not a collection of isolated symptoms—to help patients move beyond chronicity toward true healing.

01Whole-system
thinking
02Patient-defined
innovation
03Healing
at scale
ONE TEAMScience. Execution. Patient impact.
The Untech team

OUR STORY

Born from science.
Built to change healing.

Untech began with a question that medicine had left unanswered for too long: why do some wounds remain trapped in chronicity? From a university laboratory in Argentina, our founders set out to understand the wound as a complete biological system — and to create a therapy capable of changing its course.

01THE ORIGIN

A scientific insight

Research at CONICET and the National University of Tucumán reveals that chronic wounds must be treated as a complex, self-sustaining microenvironment.

02THE COMPANY

Science becomes Untech

Rubén Salim Brovia and Dr. Alberto Ramos Vernieri bring business and science together to transform that discovery into a scalable biotechnology company.

03THE BREAKTHROUGH

One product, multiple mechanisms

Years of development lead to a first-in-class topical hydrogel designed to act simultaneously on the factors that keep a wound from healing.

04THE WORLD

From Argentina to global impact

International patents, strategic partners and clinical development move Untech closer to its purpose: restoring healing and making it accessible worldwide.

We did not set out to make another dressing.
We set out to change the biology of chronic wounds.
GLOBAL VALIDATION

Global Awards
& Recognition.

Untech has been distinguished by leading institutions across science, innovation and entrepreneurship.

Partner with us

We are expanding our international presence beyond Latin America and actively seeking partners across the United States, Europe, and Asia to bring this therapy to patients worldwide.

If you are a clinician, investor, or industry partner interested in advancing the future of wound care, we would welcome the opportunity to connect.

Email: info@untech.bio
Address: Suipacha 1111, CABA, Argentina
LinkedIn: untech-bio

UNTECH topical hydrogel concept packagingCONCEPT
UNTECH · TOPICAL HYDROGEL · 30 g

Before you continue

The concept pack contains one 30 g tube of transparent topical hydrogel and product information for clinician-directed use. Chronic wounds need professional assessment and ongoing care. This product experience is a design simulation and does not constitute an offer for sale.